Challenging Cases in the Management of Bipolar Depression: What Would You Do?

Challenging Cases in the Management of Bipolar Depression: What Would You Do?

On-Demand Webcast

Manpreet K. Singh, MD, MS
Associate Professor and Akiko Yamazaki and Jerry Yang Faculty
Scholar in Pediatric Translational Medicine
Department of Psychiatry and Behavioral Sciences
Director, Pediatric Mood Disorders Program
Director, Pediatric Emotion and Resilience Lab
Stanford University School of Medicine
Stanford, California

Trisha Suppes, MD, PhD
Department of Psychiatry & Behavioral Sciences
Stanford University School of Medicine
Director, Exploratory Therapeutics Laboratory
Treasurer Elect of the American Society of Clinical Psychopharmacology
Immediate Past President of the International Society for Bipolar Disorders
Founder, VA Palo Alto Bipolar and Depression Research Program
Director, VA Palo Alto CSP NODES
VA Palo Alto Health Care System

For full faculty bios, please call 609-371-1137.



Provided by North American Center for Continuing Medical Education, LLC, an HMP Company and CMEology.

For questions regarding this educational activity, please call 609-371-1137 or email



This activity is intended for psychiatrists, primary care physicians, psychologists, physician assistants, psychiatric nurses, and other healthcare professionals who seek to improve the care of patients with mental health disorders.


After completing this activity, participants should be able to:

  • Apply evidence-based strategies for the recognition and treatment of pediatric bipolar depression
  • Discuss evidence-based approaches to the pharmacologic management of bipolar depression in adults, including adjunctive therapies
  • Describe how to identify and treat bipolar depression with mixed features
  • Implement strategies to monitor and manage metabolic comorbidities in patients with bipolar depression

To be eligible for documentation of credit, participants must participate in the full activity, and complete the evaluation form. Participants who successfully complete the evaluation form online may immediately print their documentation of credit.

Participants who have successfully completed the live version of this activity are not eligible to receive credit for this enduring material.

Release Date: 10/15/2020
Expiration Date: 10/15/2021
Estimated time to complete: 1.5 hours

For questions regarding this educational activity, please call 609-371-1137.


In support of improving patient care, North American Center for Continuing Medical Education, LLC (NACCME) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.


NACCME designates this internet live activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Physician Assistants
NACCME has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with the AAPA CME Criteria. This internet activity is designated for 1.5 AAPA Category 1 credit(s). PAs should only claim credit commensurate with the extent of their participation in the activity.


This continuing nursing education internet live activity awards 1.5 contact hours.

Provider approved by the California Board of Registered Nursing, Provider #13255, for 1.5 contact hours.


As a jointly accredited organization, North American Center for Continuing Medical Education, LLC (NACCME) is approved by the American Psychological Association to sponsor continuing education for psychologists. NACCME maintains responsibility for this program and its content. Variable credit for partial attendance may not be awarded. Full attendance is required for all CE activities.

Instructional Level: Advanced

Social Workers (ASWB ACE)

NACCME is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. State and provincial regulatory boards have the final authority to determine whether an individual course may be accepted for continuing education credit. NACCME maintains responsibility for this course. Social workers completing this course receive 1.5 Intermediate continuing education credits.


The planning committee comprises  Manpreet K. Singh, MD, MS; Trisha Suppes, MD, PhD; Douglas L. Noorsdy, MD; William C. Torrey, MD; Beth Goodwin, Rob Lowney, and Esther Langmack, MD, FCCP, CMEology; and Meaghan Benci, Christopher Bowell, Raquel Gaerlan, Samantha Conforti, Greaton Sellers, Mary Johnson, Randy Robbin, Michelle Stewart, and Kelly Sweeney, NACCME.

Independent Clinical Reviewers

The independent clinical reviewers for this activity are:

Douglas L. Noordsy, MD, Clinical Professor of Psychiatry & Behavioral Sciences, Stanford University School of Medicine; Director of Sports Psychiatry, Department of Psychiatry & Behavioral Sciences, Stanford University, Stanford, California

William C. Torrey, MD, Professor of Psychiatry; Medical Directory, Department of Psychiatry, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire

Nurse Planner

The nurse planner for this activity is Andrew Penn, RN, MS, NP, CNS, APRN-BC, Psychiatric Nurse Practitioner, Kaiser Permanente, Redwood City, California; Assistant Clinical Professor, University of California, San Francisco, California


According to the disclosure policy of NACCME, faculty, editors, managers, and other individuals who are in a position to control content are required to disclose any relevant financial relationships with relevant commercial companies related to this activity. All relevant conflicts of interest that are identified are reviewed for potential conflicts of interest. If a conflict is identified, it is the responsibility of NACCME to initiate a mechanism to resolve the conflict(s). The existence of these interests or relationships is not viewed as implying bias or decreasing the value of the presentation.

All educational materials are reviewed for fair balance, scientific objectivity of studies reported, and levels of evidence.

The faculty reported the following:

Dr. Singh: Advisory Board of Sunovion Pharmaceuticals Inc.; Consultant for Google X and Limbix; Research Grants from Brain and Behavior Research Foundation, Janssen, NIH, and PCori; Royalties for American Psychiatric Association Publishing

Dr. Suppes: Consultant for Allergan, Inc., Impel NeuroPharma Inc., Intracellular Therapies, and Sunovion Pharmaceuticals Inc.; Research Grants from Merck and Palo Alto Health Sciences; Royalties for American Psychiatric Association Publishing, Hogrefe Publishing, Jones & Bartlett, and Wolters Kluwer Health (UpToDate)

Dr. Noordsy, Mr. Penn, and Dr. Torrey have disclosed no relevant financial relationships with any commercial interests. Ms. Goodwin, Mr. Lowney, and Dr. Langmack, CMEology and Ms. Benci, Ms. Gaerlan, Ms. Johnson, Mr. Robbin, and Ms. Sweeney; NACCME have disclosed no relevant financial relationships with any commercial interests. NACCME requires faculty to inform participants whenever off-label/unapproved uses of drugs and/or devices are discussed in their presentations Off-label/unapproved uses of drugs and/or devices will be disclosed prior to the start of each session.

Chris Bolwell is a shareholder of GlaxoSmithKline. GlaxoSmithKline is not supporting this activity, nor does any content relate to their product/service.


This activity may contain information about experimental and other uses of drugs or devices that are not currently approved by the Food and Drug Administration (FDA) of the United States or European Medicines Agency (EMA). Participants are encouraged to consult the EMA-approved or FDA-approved product labeling for any drug or device mentioned in this activity before use. The opinions expressed in this document are the opinions of the presenters and do not necessarily reflect the opinions of Imedex, LLC and/or NACCME, LLC and/or CMEology, LLC.


The evaluation is accessible after the activity via a PC (Windows 7 or newer) or Mac (Mac OS 10.6 or later) computer with current versions of the following browsers: Internet Explorer, Mozilla Firefox, Google Chrome, or Safari. A PDF reader is required for print publications. Please direct technical questions to


North American Center for Continuing Medical Education (NACCME) complies with the legal requirements of the Americans with Disabilities Act and the rules and regulations thereof. If any participant in this educational activity is in need of accommodations, please call 609-371-1137


NACCME protects the privacy of personal and other information regarding participants, educational partners, and joint providers. NACCME and our joint providers will not release personally identifiable information to a third party without the individual’s consent, except such information as is required for reporting purposes to the appropriate accrediting agency. NACCME maintains physical, electronic, and procedural safeguards that comply with federal regulations to guard your nonpublic personal information.

Copyright © 2020 by North American Center for Continuing Medical Education, LLC. All rights reserved. No part of this accredited continuing education activity may be reproduced or transmitted in any form or by any means, electronic or mechanical, without first obtaining permission from North American Center for Continuing Medical Education.


Supported by an educational grant from Sunovion Pharmaceuticals Inc.