Key Insights: Mastering Clinical Challenges and Emerging Therapies in IBD 2018

Key Insights: Mastering Clinical Challenges and Emerging Therapies in IBD 2018

On-Demand Webcast

David T. Rubin, MD, FACG
University of Chicago Medicine
Chicago, Illinois


Jean-Frederic Colombel, MD
Icahn School of Medicine at Mount Sinai
New York, New York

Target Audience

This educational activity is designed for gastroenterologists, GI fellows, and other healthcare professionals (internists, primary care physicians, nurse practitioners, physician assistants, nurses, pharmacists, etc.) involved and/or interested in the therapeutic management of patients with IBD.


In this Key Insights™ activity, Drs. David T. Rubin and Jean-Frederic Colombel discuss the key take-home messages from the 2018 Mastering Clinical Challenges and Emerging Therapies in Inflammatory Bowel Disease meeting, held on July 21, 2018 in Chicago, Illinois, which focused on the interpretation of best practices and recent advancements in the management of IBD. Topics of discussion include: emerging therapies, treat-to-target, biosimilars, JAK inhibitors, and top down therapy.


Upon successful completion of this educational activity, participants should be better able to:

  1. Assess the mechanism of action and therapeutic potential of evolving treatments in IBD
  2. Evaluate strategies for sequencing therapeutics in the era of biologics, immunotherapies and biosimilars
  3. Define the role of treat-to-target in IBD regimens designed to maximize the opportunity to achieve remission and avoid relapse

This activity is provided by Imedex®, LLC.

Continuing Education


Imedex, LLC is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Imedex, LLC designates this internet-based enduring educational activity for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should claim only credit commensurate with the extent of their participation in the activity.

AAPA accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credits™ from organizations accredited by ACCME or a recognized state medical society. Physician assistants may receive a maximum of 0.5 hour of Category 1 credit for completing this program.

In order to receive credit, participants must successfully complete the post-test and complete the online evaluation form. You will receive an online CME statement of credit to print for your records.


Supported by educational grants from: AbbVie, Inc., Celgene Corporation, Pfizer, and Takeda Pharmaceuticals, U.S.A. Inc.


As a provider accredited by the Accreditation Council for Continuing Medical Education (ACCME), Imedex, LLC must ensure balance, objectivity, independence, and scientific rigor in its educational activities. Faculty are instructed to provide a balanced view of therapeutic options by utilizing generic names to ensure impartiality.

All faculty participating in an Imedex activity are required to disclose relevant financial relationships that may be considered to be related to the subject matter of the educational activity. Disclosure of these commitments and/or relationships is included in these course materials so that participants in the activity may formulate their own judgments in interpreting its content and evaluating its recommendations.

The following indicates the faculty disclosure declaration information and the nature of those commercial relationships.

1=grant/research support 2=consultant 3=speaker’s bureau 4=stock shareholder 5=other support

Jean-Frederic Colombel, MD AbbVie, Inc.1,2,3 Amgen2; Arena Pharmaceuticals2; Boehringer Ingelheim2; Celgene Corporation2,3; Celltrion2; Eli Lilly2; Enterome2; Ferring Pharmaceuticals2,3; Genefit4; Genentech2; Gilead2; Intestinal Biotech4; Janssen1,2; MedImmune2; Merck & Co.2; Nextbiotix2; Novartis Pharmaceuticals Corporation, Inc.2; Otsuka Pharmaceutical Development & Commercialization, Inc.2; Pfizer2; Protagonist2; Second Genome2; Seres Therapeutics; Shire; Takeda1,2,3; Theradiag2
David T. Rubin, MD, FACG AbbVie, Inc.1,2; Abgenomics1; Allergan, Inc.2; American College of Gastroenterology5; Amgen2; Celgene Corporation2; Cornerstones Health, Inc.5; Ferring Pharmaceuticals2; Forward Pharma2; Genentech/Roche1; GoDuRn, LLC5; Janssen Pharmaceuticals1,2; Merck & Co., Inc2; Medtronic2; Napo Pharmaceuticals2; Pfizer2; Prometheus Laboratories1; Salix Pharmaceuticals, Inc.2; Shire1,2; Takeda Pharmaceuticals1,2; Target PharmaSolutions, Inc2; UCB Pharma1

All materials are included with the permission of the authors.

Imedex, LLC Staff Disclosure of Financial Relationships
All Imedex staff members who are in a position to control content of this activity have no financial relationships with any commercial interests, except for the following individuals:

   Chris Bolwell owns shares of stock of GlaxoSmithKline.

Unapproved Uses

This activity may contain information about experimental and other uses of drugs or devices that are not currently approved by the US Food and Drug Administration (FDA) and/or other national regulatory agencies in the United States and other countries. Participants in the United States are encouraged to consult the FDA-approved product labeling for any drug or device mentioned in this program before use. Participants from other countries should consult with their respective regulatory authorities.

The opinions expressed in this webcast are the opinions of the authors and do not necessarily reflect the opinions of Imedex.


The material presented and related discussions are not intended to be medical advice, and the presentation or discussion of such material is not intended to create and does not establish a physician-patient relationship. Medical advice of any nature should be sought from an individual’s own physician.

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Imedex is a brand and assumed name used by Imedex, LLC (hereby referred to as Imedex). Imedex is solely responsible for this agenda’s content. Although Imedex attempts to ensure that the information in our program is accurate and timely, matters and opinions discussed and/or presented with respect to clinical matters are those of the discussion participants only, and not necessarily those of Imedex. Moreover, although Imedex attempts to identify and integrate the most qualified medical professionals in our program, TO THE FULLEST EXTENT PERMITTED BY LAW, IMEDEX EXPRESSLY DISCLAIM ALL WARRANTIES, EITHER EXPRESS OR IMPLIED, STATUTORY OR OTHERWISE, INCLUDING BUT NOT LIMITED TO THE IMPLIED WARRANTIES OF MERCHANTABILITY, NON-INFRINGEMENT OF THIRD PARTIES’ RIGHTS, AND FITNESS FOR A PARTICULAR PURPOSE, WITH RESPECT TO THE CONTENT PRESENTED. IMEDEX FURTHER MAKES NO REPRESENTATIONS OR WARRANTIES ABOUT THE ACCURACY, RELIABILITY, COMPLETENESS OR TIMELINESS OF THE CONTENT OR ANY MATERIAL PRESENTED.

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Release Date: July 31, 2018

Expiration Date: July 31, 2019