Reducing Clinical Inertia in Type 2 Diabetes: A Case for Early Combination Therapy

Reducing Clinical Inertia in Type 2 Diabetes: A Case for Early Combination Therapy

On-Demand Webcast

Carol H. Wysham, MD
Clinical Professor of Medicine
University of Washington
Clinical Endocrinologist
MultiCare Rockwood Diabetes and Endocrinology Center
Spokane, Washington

Intended Learners

This activity is designed for primary care physicians, family medicine specialists, internists, pediatricians, nurse practitioners, nurses, physician assistants, pharmacists, registered dietitians, certified diabetes educators, and other related healthcare professionals involved in the treatment of patients at risk for cardiometabolic syndrome. 

Learning Objectives

After completing this activity, participants should be able to:

  • Outline the benefits and risks of various classes of antihyperglycemic agents for the treatment of type 2 diabetes mellitus
  • Review current guideline recommendations for the initiation and intensification of therapy in patients with type 2 diabetes mellitus
  • Discuss the rationale, role, and potential benefits of fixed-dose combinations
  • Design individualized treatment plans for timely achievement of glycemic goals
Activity Overview

To be eligible for documentation of credit, participants must complete the educational activity, complete the 10 question post-test with a score of 70% or better, and complete the evaluation form.

After successful completion of the post-test and evaluation form online at, participants may immediately print their documentation of credit.

ACPE Credit Policy

The certificate is not the official record of your participation in the activity. The official record of credit will be the information in CPE Monitor system.

Eligibility for pharmacy credit is contingent upon the successful completion of a post-test and/or evaluation for each activity or session attended. The reporting function into CPE Monitor will only be available for 60 days after your completion of the activity.  Under ACPE Policy, NACCME will not be able to report your credit to CPE Monitor after this 60 day period.

Release Date: October 16, 2018
Expiration Date: October 16, 2019
Estimated time to complete: 45 minutes

Participants who completed the live version of this activity are not eligible to receive credit for this enduring material.

For questions regarding this educational activity, please call 609-371-1137.

There is no fee associated with this activity.

Hardware/Software Requirements

All educational activities are accessible via a PC (Windows 2000/XP/Vista/7) or Mac (Mac OS 10.x or later) computer with current versions of the following browsers: Internet Explorer, Mozilla Firefox, Google Chrome, or Safari. Windows Media Player or compatible alternative, sound card, and speakers are required for streamed audio. The latest version of the Adobe Flash Player is suggested for video programs (please download here). A PDF reader is required for print publications. Please direct technical questions to


    In support of improving patient care, North American Center for Continuing Medical Education (NACCME) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.



NACCME designates this enduring material for a maximum of .75 AMA PRA Category 1 Credit™.

Physicians should claim only the credit commensurate with the extent of their participation in the activity.


NACCME has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with the AAPA CME Criteria. This activity is designated for 0.75 AAPA Category 1 credit(s).

PAs should only claim credit commensurate with the extent of their participation.


This enduring activity is approved for .75 contact hour (.075 CEUs) of continuing pharmacy education (UAN JA0006201-9999-18-195-H01-P).

This educational activity is a knowledge-based activity.

Any participant wanting to file a grievance with respect to any aspect of a continuing pharmacy education activity accredited by NACCME may contact the Senior Manager, Accreditation & Compliance, NACCME, in writing at 104 Windsor Center Drive, East Windsor, NJ 08520. The Senior Manager, Accreditation & Compliance will review the grievance and respond within 30 days of receiving the written statement. If the participant is unsatisfied with the response, an appeal to the Senior Director, Accreditation and Compliance, NACCME, may be made for a second level of review.

Planning Committee

The planning committee is comprised of Michael Bloch, MD; Daniel Einhorn, MD; Timothy Harlan, MD; Peter H. Jones, MD; Jeffrey Levine, MD; Margo Minissian, PhD, ACNP; Leah Sarris, BS; Edward Shahady, MD; and Brian Lee, PharmD, Katie Oakes, HorizonCME, and Donna Brophy, MaryEllen Fama, Emily Gibson, Jennifer Ilcyn, Mary Johnson, Todd Kunkler, Randy Robbin, Susan Yarbrough, NACCME.

Independent Clinical Reviewer: Lorena Alarcon Casas Wright, MD, Clinical Associate Professor, University of Washington School of Medicine/Endocrinology, University of Washington Medical Center/Roosevelt, Seattle, Washington.

Financial Disclosure and Conflicts of Interest

According to the disclosure policy of NACCME, faculty, editors, managers, and other individuals who are in a position to control content are required to disclose any relevant financial relationships with relevant commercial companies related to this activity. All relevant conflicts of interest that are identified are reviewed for potential conflicts of interest. If a conflict is identified, it is the responsibility of NACCME to initiate a mechanism to resolve the conflict(s). The existence of these interests or relationships is not viewed as implying bias or decreasing the value of the presentation.

All educational materials are reviewed for fair balance, scientific objectivity of studies reported, and levels of evidence.

Dr. Wright and Dr. Wysham have disclosed no relevant financial relationships with any commercial interests.

Brian Lee, PharmD, Katie Oakes, HorizonCME, and Donna Brophy, MaryEllen Fama, Emily Gibson, Jennifer Ilcyn, Mary Johnson, Todd Kunkler, Randy Robbin, Susan Yarbrough disclosed no relevant financial relationships with any commercial interests.

NACCME requires faculty to inform participants whenever off-label/unapproved uses of drugs and/or devices are discussed in their presentations.

The faculty has disclosed no off-label/unapproved use(s) of drugs and/or devices will be discussed.

Privacy Policy

NACCME protects the privacy of personal and other information regarding participants, educational partners, and joint sponsors. NACCME and our joint sponsors will not release personally identifiable information to a third party without the individual's consent, except such information as is required for reporting purposes to the appropriate accrediting agency.

NACCME maintains physical, electronic, and procedural safeguards that comply with federal regulations to guard your nonpublic personal information.

Copyright © 2018 by North American Center for Continuing Medical Education, LLC. All rights reserved. No part of this accredited continuing education activity may be reproduced or transmitted in any form or by any means, electronic or mechanical, without first obtaining permission from North American Center for Continuing Medical Education. The opinions expressed in this educational activity are those of the faculty and are not attributable to NACCME. Clinical judgment must guide each professional in weighing the benefits of treatment against the risk of toxicity. Dosages, indications, and methods of use for products referred to in this activity are not necessarily the same as indicated in the package insert for each product, may reflect the clinical experience of the presenters, and may be derived from the professional literature or other clinical sources. Consult complete prescribing information before administering.

Grant Support

This activity is supported by an educational grant from Merck. Jointly provided by North American Center for Continuing Medical Education, LLC, an HMP Company and Horizon CME.