The Role of Factor Xa Anticoagulation in CLI

The Role of Factor Xa Anticoagulation in CLI

On-Demand Webcast

Richard Neville, MD
INOVA Health System
Falls Church, Virginia

Fadi Saab, MD, FACC, FSCAI
Advanced Cardiac & Vascular Amputation Prevention Centers
Grand Rapids, Michigan

Craig Walker, MD
Tulane Medical School
Cardiovascular Institute of the South
Houma, Lousiana

Intended Learners

Interventional cardiologists, vascular surgeons, interventional radiologists, wound care specialists, podiatrists, nurses, vascular technologists, and cardiovascular catheterization laboratory team members.

Learning Objectives

After completing this activity, participants should be able to:

  • Assess the efficacy of factor Xa anticoagulation in combination with aspirin to prevent MALE
  • Analyze efficacy and safety findings from clinical trials of factor Xa anticoagulants in PAD 
  • Determine which PAD patients might be optimal candidates for therapy with low-dose factor Xa anticoagulation + aspirin
Activity Overview

This on-demand webcast is available with synchronized slides and audio.

To be eligible for documentation of credit, participants must complete the educational activity, complete the post-test with a score of 75% or better, and complete the evaluation form. After successful completion of the post-test and evaluation form online at, participants may immediately print their documentation of credit.

Release Date: August 30, 2018
Expiration Date: August 30, 2019
Estimated time to complete: 1 hour

There is no fee associated with this activity.

For questions regarding this educational activity, please call 609-371-1137.

Participants who have successfully completed the live version of this activity are not eligible to receive credit for this enduring webcast.

Accreditation Information

In support of improving patient care, North American Center for Continuing Medical Education (NACCME) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.


NACCME designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


NACCME has been authorized by the American Academy of PAs (APA) to award AAPA Category 1 CME credit for activities planned in accordance with the AAPA CME Criteria. This activity is designated for 1 AAPA Category 1 credit. PAs should only claim credit commensurate with the extent of their participation.


This continuing nursing education activity awards 1 contact hours.

Provider approved by the California Board of Registered Nursing, Provider #13255 for 1 contact hour.


North American Center for Continuing Medical Education, LLC (NACCME) is approved by the Council on Podiatric Medical Education as a provider of continuing education in podiatric medicine. NACCME has approved this activity for a maximum of 1 continuing education contact hours.


Eligible Amputation Prevention Symposium sessions have been approved for 1 ARRT Category A CE credits by AHRA. Program Approval Start Date: 8/31/2018; Program Approval End Date: 8/31/2019 

Planning Committee

The planning committee comprises Craig Walker, MD; Richard Neville, MD; Fadi Saab, MD, FACC, FSCAI; Robert S. Dieter, MD, RVT, FACC; Susie Seaman, NP; Susan Yarbrough, Imedex; and MaryEllen Fama, Caitlin Eastman, Emily Gibson, Jennifer Ilcyn, Randy Robbin, and Colleen Waters, NACCME.

Independent Clinical Reviewer: Robert S. Dieter, MD, RVT, FACC, Loyola University Medicine, Chicago, Illinois

Nurse Planner: Susie Seaman, NP, Sharp Rees-Stealy Wound Clinic, San Diego, California

Financial Disclosure and Conflicts of Interest

According to the disclosure policy of NACCME, faculty, editors, managers, and other individuals who are in a position to control content are required to disclose any relevant financial relationships with relevant commercial companies related to this activity. All relevant conflicts of interest that are identified are reviewed for potential conflicts of interest. If a conflict is identified, it is the responsibility of NACCME to initiate a mechanism to resolve the conflict(s). The existence of these interests or relationships is not viewed as implying bias or decreasing the value of the presentation.

All educational materials are reviewed for fair balance, scientific objectivity of studies reported, and levels of evidence.

The faculty has reported the following: 

Dr. Neville: Consultant—CorMatrix, Gore, Tissue Analytics, Inc.; Speakers’ Bureau—GraftWorx

Dr. Saab: Consultant - Abbott Vascular, Bard Peripheral Vascular, Boston Scientific, Cardiovascular Systems, Inc., Medtronic, Philips/Spectranetics, Terumo

Dr. Walker: Consultant – Abbott, Boston Scientific, Cardiva, CR Bard, Lake Regional Medical, Medtronic, Philips/Volcano; Speaker’s Bureau – Abbott, Bard, Bristol-Myers-Squibb/Sanofi, Cardiva, Janssen, Philips/Volcano, W.L. Gore; Major Stock Shareholder – Cardiva; PVD Training – Abbott, Bard, Boston Scientific, Philips/Volcano

Ms. Seaman: Scientific Advisor—Healthpoint BioTherapeutics, Mölnlycke Health Care; Speakers' Bureau—Mölnlycke Health Care

Dr. Dieter, Susan Yarbrough, MaryEllen Fama, Caitlin Eastman, Emily Gibson, Jennifer Ilcyn, Randy Robbin, and Colleen Waters have disclosed no relevant financial relationships with any commercial interests.

Brand Name and Device Disclosure

This continuing education activity may include device or medication brand names as a means to improve clarity for participants only, due to the presence of differently branded versions of the same device, agent, or service. No promotion or recommendations should be inferred. All educational materials are reviewed for fair balance, scientific objectivity of studies reported, and levels of evidence.

Hardware/Software Requirements

The evaluation is accessible after the activity via a PC (Windows 2000/XP/Vista/7) or Mac (Mac OS 10.x or later) computer with current versions of the following browsers: Internet Explorer, Mozilla Firefox, Google Chrome, or Safari. A PDF reader is required for print publications. Please direct technical questions to

ADA Statement

North American Center for Continuing Medical Education complies with the legal requirements of the Americans with Disabilities Act and the rules and regulations thereof. If any participant in this educational activity is in need of accommodations, please call 609-371-1137.

Privacy Policy

NACCME protects the privacy of personal and other information regarding participants, educational partners, and joint sponsors. NACCME and our joint sponsors will not release personally identifiable information to a third party without the individual's consent, except such information as is required for reporting purposes to the appropriate accrediting agency.

NACCME maintains physical, electronic, and procedural safeguards that comply with federal regulations to guard your nonpublic personal information.

Copyright © 2018 by North American Center for Continuing Medical Education, LLC. All rights reserved. No part of this accredited continuing education activity may be reproduced or transmitted in any form or by any means, electronic or mechanical, without first obtaining permission from North American Center for Continuing Medical Education. The opinions expressed in this educational activity are those of the faculty and are not attributable to NACCME. Clinical judgment must guide each professional in weighing the benefits of treatment against the risk of toxicity. Dosages, indications, and methods of use for products referred to in this activity are not necessarily the same as indicated in the package insert for each product, may reflect the clinical experience of the presenters, and may be derived from the professional literature or other clinical sources. Consult complete prescribing information before administering.

Provided by North American Center for Continuing Medical Education, LLC, An HMP Company.

Grant Support

This activity is supported by an educational grant from Janssen Scientific Affairs, LLC.