Stimulating Granulation Tissue in Wounds with Instillation: A Guide to Wound Bed Preparation

On-Demand Webcast

John S. Steinberg, DPM
Associate Professor
Georgetown University School of Medicine
Co-Director of Wound Center
Department of Plastic Surgery
MedStar Georgetown University Hospital
Residency Director
Podiatric Medicine and Surgery
MedStar Washington Hospital Center
Washington, DC

Tom Wolvos, MD, FACS
Chairman, Division of General Surgery
Scottsdale Healthcare
Osborn Medical Center
Scottsdale, Arizona

Learning Objectives

After completing this activity, participants should be able to:

  • Describe the role of wound bed preparation to facilitate normal endogenous processes of healing and enhance the effects of advanced therapies in the management of wounds
  • Describe the role of debridement in the wound bed preparation cycle and determine the most effective method based on the status of the wound
  • Evaluate the effectiveness of negative-pressure wound therapy in promoting granulation tissue in chronic wounds
  • Review the role of wound cleansing in wound bed preparation and compare and contrast cleansing techniques and solutions
  • Review clinical evidence supporting the use of instillation therapy in managing a variety of wound types
Intended Learners

This activity is designed for physicians, podiatrists, pharmacists, nurses, and physical therapists involved in wound healing or wound care issues.

Activity Overview

This on-demand webcast is available with synchronized slides and video.

To be eligible for documentation of credit, participants must complete the educational activity, complete the 10-question online post-test with a score of 70% or better, and complete the evaluation form.

ACPE Credit Policy

Your official record of ACPE credit will be generated through the CPE Monitor System. The certificate printed from this website after completing the evaluation for this activity is for personal tracking purposes only.

Eligibility for pharmacy credit is contingent upon the successful completion of a post-test and/or evaluation for each activity or session attended. Please note that you must complete the activity evaluation within 60 days of a live activity or within 60 days of beginning the evaluation for an enduring activity. Under ACPE Policy, NACCME will not be able to report your activity completion to CPE Monitor after this 60-day period.

After successful completion of the post-test and evaluation form online at, participants may immediately print their documentation of credit.

Participants who have successfully completed the live version of this activity are not eligible to receive credit for this enduring material.

Date of last review: October 27, 2016
Release date: March 31, 2014
Expiration date: January 31, 2021
Date of last review: January 31, 2020

Estimated time to complete: 1 hour

There is no fee associated with this activity.
For questions regarding this educational activity, please call 609-371-1137.

Hardware/Software Requirements

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In support of improving patient care, North American Center for Continuing Medical Education (NACCME) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.


NACCME designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


This continuing nursing education activity awards 1.0 contact hour.

Provider approved by the California Board of Registered Nursing, Provider #13255 for 1.0 contact hour.


This educational activity is approved for 1 contact hour (0.1 CEU) of continuing pharmacy education (UAN:JA0006201-0000-20-061-H01-P)

This Educational Activity is a Knowledge-Based Activity.

Any participant wanting to file a grievance with respect to any aspect of a continuing pharmacy education activity accredited by NACCME may contact the Senior Manager, Accreditation & Compliance, NACCME, in writing at 104 Windsor Center Drive, East Windsor, NJ 08520. The Senior Manager, Accreditation & Compliance will review the grievance and respond within 30 days of receiving the written statement. If the participant is unsatisfied with the response, an appeal to the Senior Director, Accreditation and Compliance, NACCME, may be made for a second level of review.

Continuing Podiatric Education

North American Center for Continuing Medical Education, LLC (NACCME) is approved by the Council on Podiatric Medical Education as a provider of continuing education in podiatric medicine. NACCME has approved this activity for a maximum of 1.0 continuing education contact hour.

Independent clinical reviewer:Daniel Federman, MD, FACP, Yale University School of Medicine, Newton, Connecticut

Nurse planner: Susie Seaman, NP, Sharp Rees-Stealy Wound Clinic, San Diego, California

Planning Committee

The planning committee comprises Daniel Federman, MD, FACP, Paul J. Kim, DPM, Susie Seaman, NP, John S. Steinberg, DPM, Tom Wolvos, MD, FACS; and Kristin Ciszeski, Lauren DeFillippo, Ed Jackson, MD, Tiffney Oliver, Randy Robbin, and John Savage, NACCME.

Financial Disclosure and Conflicts of Interest

According to the disclosure policy of NACCME, faculty, editors, managers, and other individuals who are in a position to control content are required to disclose any relevant financial relationships with relevant commercial companies related to this activity. All relevant conflicts of interest that are identified are reviewed for potential conflicts of interest. If a conflict is identified, it is the responsibility of NACCME to initiate a mechanism to resolve the conflict(s). The existence of these interests or relationships is not viewed as implying bias or decreasing the value of the presentation.

All educational materials are reviewed for fair balance, scientific objectivity of studies reported, and levels of evidence.

The faculty have reported the following:

Dr. Kim: Consultant—Kinetic Concepts, Inc., Integra Lifesciences, Kimberly Clark
Ms. Seaman: Scientific advisor—Mölnlycke Health Care, Coloplast, Smith & Nephew, Inc.; Promotional Speakers’ Bureau—Mölnlycke Health Care
Dr. Federman, Dr. Steinberg, and Dr. Wolvos have disclosed no relevant financial relationships with any commercial interest

Ms. Ciszeski, Ms. DeFillippo, Dr. Jackson, Ms. Oliver, Mr. Robbin, and Mr. Savage have disclosed no relevant financial relationships with any commercial interest.

NACCME requires faculty to inform participants whenever off-label/unapproved uses of drugs and/or devices are discussed in their presentations.

The faculty have disclosed that the following off-label/unapproved drugs and/or devices will be discussed: antibiotics for the purpose of wound irrigation.

Privacy Policy

NACCME protects the privacy of personal and other information regarding participants, educational partners, and joint sponsors. NACCME and our joint sponsors will not release personally identifiable information to a third party without the individual's consent, except such information as is required for reporting purposes to the appropriate accrediting agency.

NACCME maintains physical, electronic, and procedural safeguards that comply with federal regulations to guard your nonpublic personal information.

Copyright © 2017 by North American Center for Continuing Medical Education, LLC. All rights reserved. No part of this accredited continuing education activity may be reproduced or transmitted in any form or by any means, electronic or mechanical, without first obtaining permission from North American Center for Continuing Medical Education. The opinions expressed in this educational activity are those of the faculty and are not attributable to NACCME. Clinical judgment must guide each professional in weighing the benefits of treatment against the risk of toxicity. Dosages, indications, and methods of use for products referred to in this activity are not necessarily the same as indicated in the package insert for each product, may reflect the clinical experience of the presenters, and may be derived from the professional literature or other clinical sources. Consult complete prescribing information before administering.

Grant Support

Supported by an educational grant from Acelity.

1.00 CME
1.00 CNE
1.00 CPE
1.00 CPME
1.00 Participation