Genes, Germs, and Grief: The Role of Folate at the Intersection of Inflammation, Obesity, and Depression

Genes, Germs, and Grief: The Role of Folate at the Intersection of Inflammation, Obesity, and Depression

On-Demand Webcast

To access the webcast, please click here.

Upon launching the webcast, you will be redirected to http://www.medscape.org/viewarticle/776038 where you will need to either create or log into your Medscape account. All program components will be completed on the Medscape site.

Faculty

Rakesh Jain, MD, MPH
Director of Psychiatric Drug Research
R/D Clinical Research Center
Lake Jackson, TX
Associate Clinical Professor
Department of Psychiatry and Behavioral Sciences
University of Texas Medical School at Houston
Houston, TX

Vladimir Maletic, MD, MS
Clinical Professor of Neuropsychiatry and Behavioral Science
University of South Carolina School of Medicine
Columbia, SC
Consulting Associate
Division of Child and Adolescent Psychiatry
Department of Psychiatry
Duke University
Durham, NC

Charles Raison, MD
Associate Professor
Department of Psychiatry
University of Arizona College of Medicine
Barry and Janet Lang Associate Professor
John and Doris Norton School of Family and Consumer Sciences
University of Arizona
Tucson, AZ
Mental Health Expert/Mind-Body Consultant
CNNHealth.com
Scientific President
European Association of Clinical Psychoneuroimmunology

Intended Learners

This activity was developed for psychiatrists, primary care physicians, psychiatric nurses, psychologists, and other healthcare professionals who seek to improve their care for patients with mental health disorders and the outcomes resulting in that care.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Consider the existing data surrounding the use of folate-based therapies for major depressive disorder (MDD) when determining treatment plans for patients
  • Identify specific clinical scenarios and patient profiles in which utilizing folate-based therapies would be appropriate for the treatment of patients with MDD
  • Devise and incorporate personalized approaches to the overall treatment plan for patients with MDD
Activity Overview

This activity is designed to be completed within the time designated on the title page; participants should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit:

  1. Upon launching the webcast, you will be redirected to http://www.medscape.org/viewarticle/776038 where you will need to either create or log into your Medscape account. All program components will be completed on the Medscape site. 
  2. Read the intended learners, learning objectives, and author disclosures.
  3. Study the educational content online.
  4. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. In addition, you must complete the Activity Evaluation to provide feedback for future programming.

Participants who have successfully completed the live version of this activity are not eligible to receive credit for this enduring material.

Release Date: December 20, 2012
Expiration Date: December 20, 2013
Estimated time to complete: 60 minutes

For CME/CE questions regarding this educational activity, please call 609-371-1137.
For technical assistance, please contact CME@medscape.net.
This educational activity is a knowledge-based activity.

Hardware/Software Requirements

To access activities, users will need:

  • A computer with an Internet connection.
  • Internet Explorer 7.x or higher, Firefox 4.x or higher, Safari 2.x or higher, or any other W3C standards compliant browser.
  • Adobe Flash Player and/or an HTML5 capable browser may be required for video or audio playback.
  • Occasionally other additional software may be required such as PowerPoint or Adobe Acrobat Reader.
Accreditation

In support of improving patient care, North American Center for Continuing Medical Education, LLC (NACCME) is accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

CME

NACCME designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CNE

This continuing nursing education activity awards 1.0 contact hour.

Provider approved by the California Board of Registered Nursing, Provider #13255 for 1.0 contact hour.

CPE

This activity is approved for 1 contact hour (0.1 CEU) of continuing pharmacy education (UAN 0276-0000-13-028-H01-P).

Release date: January 24, 2013

Any participant wanting to file a grievance with respect to any aspect of a continuing pharmacy education activity accredited by NACCME may contact the Assistant Director, Accreditation Services, NACCME, in writing at 300 Rike Drive, Suite A, Millstone Township, NJ 08535. The Assistant Director, Accreditation Services will review the grievance and respond within 30 days of receiving the written statement. If the participant is unsatisfied with the response, an appeal to the Executive Director, Accreditation Services, NACCME, may be made for a second level of review.

APA

North American Center for Continuing Medical Education, LLC (NACCME) is approved by the American Psychological Association to sponsor continuing education for psychologists. NACCME maintains responsibility for this program and its content.

Physician assistants, nurse practitioners, and nurses may participate in this educational activity and earn a certificate of completion, as AAPA, AANP, and ANCC accept AMA PRA Category 1 Credits™ through their reciprocity agreements.

Nurse Planner: Andrew Penn, RN, MS, NP, CNS, Psychiatric Nurse Practitioner, Kaiser Permanente, Redwood City, CA; Assistant Clinical Professor, University of California, San Francisco, San Francisco, CA

Planning Committee

The planning committee comprises Rakesh Jain, MD, MPH, Vladimir Maletic, MD, MS, Andrew Penn, RN, MS, NP, CNS, Charles Raison, MD; and Kristin Ciszeski, Lauren DeFillippo, Kristin Della Volpe, Raquel Gaerlan, Randy Robbin, Lynn Rubin, and Sue Ellen Touma, PhD, NACCME.

Financial Disclosure and Conflicts of Interest

According to the disclosure policy of NACCME, faculty, editors, managers, and other individuals who are in a position to control content are required to disclose any relevant financial relationships with relevant commercial companies related to this activity. All relevant conflicts of interest that are identified are reviewed for potential conflicts of interest. If a conflict is identified, it is the responsibility of NACCME to initiate a mechanism to resolve the conflict(s). The existence of these interests or relationships is not viewed as implying bias or decreasing the value of the presentation.

All educational materials are reviewed for fair balance, scientific objectivity of studies reported, and levels of evidence.

Rakesh Jain, MD, MPH, is on the speakers bureau for Forest Laboratories Inc., Pfizer Inc., Pamlab LLC, and Eli Lilly and Company, and is a consultant for Forest Laboratories Inc., Pfizer Inc., Pamlab LLC, and Eli Lilly and Company. He also obtains research support from Forest Laboratories Inc., Pfizer Inc., and Eli Lilly and Company.

Vladimir Maletic, MD, MS, is a consultant for Cephalon Inc., Eli Lilly and Company, Pamlab Inc., Shionogi Inc., Sunovion Pharmaceuticals Inc., Takeda Pharmaceutical Co Ltd, and Teva Pharmaceutical Industries Ltd. He is a speaker for Cephalon Inc., Merck & Co Inc., Pamlab Inc., Shionogi Inc., Sunovion Pharmaceuticals Inc., and Teva Pharmaceutical Industries Ltd.

Andrew Penn, RN, MS, NP, CNS, has disclosed no relevant financial relationships with any commercial interests.

Charles Raison, MD, is on the advisory board for Biodex Therapeutics, Bristol-Myers Squibb Company, and Pamlab LLC. He is also a speaker for Pamlab LLC.

Ms. Ciszeski, Ms. DeFillippo, Ms. Volpe, Ms. Gaerlan, Mr. Robbin, Ms. Rubin, and Dr. Touma have disclosed no relevant financial relationships with any commercial interests.

North American Center for Continuing Medical Education, LLC (NACCME) requires faculty to inform participants whenever off-label/unapproved uses of drugs and/or devices are discussed in their presentations.

The faculty have disclosed the following off-label/unapproved uses of drugs and/or devices will be discussed: infliximab, folic acid, leucovorin, and lithium carbonate for the treatment of MDD.

This activity has been independently reviewed by CME Peer Review LLC.

Privacy Policy

NACCME protects the privacy of personal and other information regarding participants, educational partners, and joint sponsors. NACCME and our joint sponsors will not release personally identifiable information to a third party without the individual's consent, except such information as is required for reporting purposes to the appropriate accrediting agency.

NACCME maintains physical, electronic, and procedural safeguards that comply with federal regulations to guard your nonpublic personal information.

Copyright © 2012 by North American Center for Continuing Medical Education, LLC. All rights reserved. No part of this accredited continuing education activity may be reproduced or transmitted in any form or by any means, electronic or mechanical, without first obtaining permission from North American Center for Continuing Medical Education. The opinions expressed in this educational activity are those of the faculty and are not attributable to NACCME. Clinical judgment must guide each professional in weighing the benefits of treatment against the risk of toxicity. Dosages, indications, and methods of use for products referred to in this activity are not necessarily the same as indicated in the package insert for each product, may reflect the clinical experience of the presenters, and may be derived from the professional literature or other clinical sources. Consult complete prescribing information before administering.

Grant Support

This activity is supported by an educational grant from Pamlab, LLC.